| Bextra (Valdecoxib) has proven highly efficient
in treating primary dysmenorrhea (severe female menstrual
pain) and both osteoarthritis and rheumatoid arthritis.
However, Bextra can produce severe even
dangerous side-effects in some people, so for senior citizen
arthritic conditions we strongly recommend Celebrex
instead. In addition we believe Bextra should only be used
to treat primary dysmenorrhea only if Tramadol
/ Ultram has been tried but has not been effective enough.
Bextra Warning
For most women suffering from primary dysmenorrhea,
Bextra is a well tolerated and extremely effective pain
killer. However, a very small percentage of people will
suffer a reaction to this drug and it should be immediately
discontinued at the first appearance of skin rash, mucosal
lesions, or any other sign of hypersensitivity.
The following Internet pharmacies may sell genuine branded
Bextra or generic bextra AKA Valdecoxib or both. Below are
the prices, availability and links to the three pharmacies
we work with. To understand the processes and benefits of
dealing with a pharmacy in the EU or USA, please visit our
USA Customers or
International
Customers pages, depending on where you live.
| Bextra |
30
Pill Cost |
In
Stock? |
Pharmacy
Order Links |
| Pharmacy
1 |
$91.00 |
Yes |
|
| Pharmacy
2 |
N/A |
No |
N/A |
| Pharmacy
3 |
N/A |
No |
N/A |
Yes, the above pharmacies offer different quantity options
for Bextra / Valdecoxib primary dysmenorrhea pain relief
pills.
Internet Pharmacies 1 & 2 are for everyone; USA &
worldwide. They do not require your physician's name / contact
data.
Web Pharmacy 3 is for US residents only: please note, under
Federal law they may require your physicians name and contact
information, and they make be required to contact them.
Bextra was evaluated for treatment of the signs and symptoms
of osteoarthritis of the knee or hip, in five double-blind,
randomized, controlled trials in which 3918 patients were
treated for 3 to 6 months. Bextra was shown to be superior
to placebo in improvement in three domains of osteoarthritis
symptoms: (1) the Western Ontario and McMaster Universities
osteoarthritis index, a composite of pain, stiffness and
functional measures in osteoarthritis, (2) the overall patient
assessment of pain, and (3) the overall patient global assessment.
The two 3-month pivotal trials in osteoarthritis generally
showed changes statistically significantly different from
placebo, and comparable to the naproxen control, in measures
of these domains for the 10 mg/day dose. No additional benefit
was seen with a valdecoxib 20-mg daily dose.
Rheumatoid Arthritis
Bextra demonstrated significant reduction compared to placebo
in the signs and symptoms of rheumatoid arthritis, as measured
by the American College of Rheumatology a composite defined
as both improvement of 20% in the number of tender and number
of swollen joints, and a 20% improvement in three of the
following five: patient global, physician global, patient
pain, patient function assessment, and C-reactive protein.
Bextra was evaluated for treatment of the signs and symptoms
of rheumatoid arthritis in four double-blind, randomized,
controlled studies in which 3444 patients were treated for
3 to 6 months. The two 3-month pivotal trials compared valdecoxib
to naproxen and placebo.
The results for the ACR20 responses in these trials are
shown below (Table 2). Trials of Bextra in rheumatoid arthritis
allowed concomitant use of corticosteroids and/or disease-modifying
anti-rheumatic drugs, such as methotrexate, gold salts,
and hydroxychloroquine. No additional benefit was seen with
a valdecoxib 20-mg daily dose.
In 2004 in the USA alone, 6.0 million people were current
users of psychotherapeutic drugs taken non-medically (2.5
percent). These include 4.4 million who used pain relievers,
1.6 million who used tranquilizers, 1.2 million who used
stimulants, and 0.3 million who used sedatives. It is therefore
important to buy effective medications manufactured to strict
US FDA and EU regulatory guidelines, such as our pharmacies
are constrained to when they offer Bextra / Valdecoxib severe
menstrual pain relief pills. |